What is Ligandrol (Ligandrol LGD-4033) – imuscle UK

What is Ligandrol (Ligandrol LGD-4033)

Ligandrol, also known as LGD-4033, Anabolicum and VK5211, is a relatively newly discovered selective androgen receptor modulator that is taken orally.

It works similarly to anabolic steroids, but is essentially different from them. The similarity is that it makes the muscles grow and recover faster. The difference is that it successfully recognizes where the muscles are and works concentrated with them without affecting other parts of the human body, therefore it does not come hand in hand with the unpleasant side effects.

Ligandrol LGD4033 is used worldwide to increase lean muscle mass and improve overall well-being, as well as for smooth recovery after heavy training. Its original purpose, however, was as a cure for osteoporosis.

Who discovers Ligandrol?

The biopharmaceutical company Ligand Pharmaceuticals, located in the state of California, discovered Ligandrol LGD-4033 in 2009. Its great potential was noticed from the very beginning. The effect of this SARM on humans was investigated later in 2013.

The first clinical tests show that Ligandrol LGD-4033 is safe, and only two years later, the substance is available online. The most recent official data on its action and side effects are from 2018. LGD-4033 was developed and continues to be developed for therapeutic purposes by Viking Therapeutics.

VK5211 Ligandrol is recommended for people suffering from osteoporosis and other diseases that cause muscle weakness. It is used after fractures and improves bone density by activating androgen receptors.

Is LGD4033 a doping?

The World Anti-Doping Agency launched LGD-4033 in June 2015. in samples of athletes, and more interestingly, he was present in the results of tests and racehorses.

It is clear that its function is to quickly develop and strengthen muscles, increase strength and endurance. This effect on the body includes it in the list of banned substances of the world organization.

LGD-4033 is on the doping list and, according to the general opinion, has an unfair advantage, so if you do sports professionally, think carefully about when you can take Ligandrol so that it is not caught by the doping control.

What are the benefits of Ligandrol LGD-4033

The benefits of LGD-4033 in and out of the hall are many, and here are some of them:

LGD-4033 Increases muscle mass by up to 4 kg. in less than a month

Ligandrol binds extremely rapidly to the androgen receptor like other SARMs, but is considered the most anabolic of them all. With it you can gain up to 4 kg. muscle mass in less than a month without having to clean fat afterwards.

Ligandrol strengthens bones and muscles, which prevents injuries

The second most popular benefit of SARM LGD-4033 was found by a study by Viking Pharmaceuticals. The company proves that Anabolicum helps the recovery process in elderly people who have suffered a fracture of the femoral neck or suffer from osteoporosis.

During the study, it became clear that this selective androgen receptor modulator shows good results as a means of maintaining healthy bones and works well in people with cancer who are prone to losing muscle mass.

LGD4033 gives maximum strength for heavy training as well as muscular endurance

Ligandrol (LGD-4033) gives the incredible advantage of training in the gym with three times more strength without resorting to anabolic steroids.

Many fitness and bodybuilding enthusiasts use it as a means of increasing endurance during heavier workouts, where the emphasis is on weaker muscle groups.

Who is Ligandrol LGD-4033 suitable for?

Ligandrol LGD-4033 is suitable for people who need a rapid increase in strength and muscle mass, but do not want to resort to steroid hormones.

  • Ligandrol (Anabolicum) is suitable for people who train to achieve a good appearance and will appeal to anyone who wants to sculpt their body for the sake of aesthetics.
  • For people who want fast and lasting results
  • Ligandrol can be a good choice for people who are worried about accidents during exercise. Taking it will have a beneficial effect on bone structure and is believed to reduce the risk of injuries in the gym.
  • People involved in bodybuilding and other power sports

This SARM lgd-4033 is not suitable for professional athletes because, as mentioned, it is considered doping due to its strong action.

How does Ligandrol LGD-4033 work?

How Ligandrol LGD-4033 works

Ligandrol LGD-4033 acts by selectively binding to androgen receptors, which are responsible for muscle and bone tissue, to begin the regeneration process. It causes a steroid-like effect (especially testosterone), and is one of the strongest anabolic activities from the SARM supplement family.

This all sounds great, but despite the encouraging results, the mechanism by which androgens increase muscle mass remains a mystery. The fact is, however, that its effect on muscle fibers is more than remarkable. Unlike testosterone, Ligandrol does not work at the expense of the liver, prostate and sebaceous glands.

For this reason, many athletes choose the LGD-4033 as their helper on the path to achieving the perfect body and the desire for greater endurance during training.

What research shows with Ligandrol LGD-4033

In initial animal studies, Ligandrol LGD-4033 demonstrated anabolic action on muscle and bone, and selectivity to these tissues without affecting the prostate.

Later, to understand its effects in humans, Ligand Pharmaceuticals sponsored a study with 76 non-smoking men with no comorbidities between the ages of 21-50. They were given Ligandrol daily for 21 days.

During this time, all the necessary tests are performed weekly to monitor their health. Then it became clear that to some extent SARM LGD4033 suppresses its own testosterone production in humans. If you are wondering - yes, post-cycle therapy with it is needed!

However, no serious side effects have been observed with Ligandrol. This is good news for anyone who does not want to resort to steroids precisely because of the bad consequences.

Apparently, the participants in the experiment have increased their muscle mass, and many of them demonstrate better endurance to physical exertion. It is important to mention that the study was aimed at checking whether this SARM is safe rather than confirming its great efficacy.

When are the first results of Ligandrol seen

The first results of Ligandrol are seen after the third week of taking it. You will first notice an increase in muscle mass. Of course, a dramatic change for such a period can be expected only if diligence is made in the hall as well.

Most people notice the "wow" effect after the 4th week. In addition to the change in muscle mass, the body looks more inflated and massive than before. A total of 8 weeks followed by rest is the golden mean for the overall effect of Ligandrol LGD 4033.

This often inspires users to continue the cycle with LGD, but the maximum should not exceed 10 weeks. It is enough to take Ligandrol once a day to have an effect. Small doses also lead to amazing results when combined with perseverance in the gym.

Does Ligandrol act on testosterone production?

As already mentioned, Ligandrol acts on testosterone production to some extent. Although LGD-4033 is much safer than steroids, it is just as strong, which reflects on the hormone's own production during intake.

Following the recommended doses and duration of the cycle will ensure successful recovery. With post-cycle therapy, it will be easy to get your testosterone back to normal.

The optimal intake to avoid this unpleasant effect of Ligandrol is 6-8 weeks. However long you decide to use it, post-cycle testosterone booster therapy is a must, even if only with herbs.

How to cycle with Ligandrol LGD-4033

This is one of the most pleasant SARM supplements to take. Why are we of this opinion? LGD-4033 has a half-life of up to 24 hours. This means that its effect lasts all day and there is no benefit in taking it several times a day.

Ligandrol can be used by men and women with slight modifications to the dose and duration of the cycle. The intake is best to be at least half an hour before training. You will feel its effect on average 40 minutes later.

Men can take LGD-4033 at 5-10mg. once a day for 6 to 10 weeks. If you are new to the field, due to its strong action, we recommend starting with a minimum number.

The female part of the users should take half the dose for men. In a maximum period of 8 weeks, they can take 2.5 - 5 mg. LGD per day.

Muscle mass cycle

 Ligandrol LGD-4033 for muscle mass

You will not have any problems gaining muscle mass during a cycle with Ligandrol. In fact, even in small doses, this remains its most pronounced effect.

The optimal period of the cycle is 8 weeks, and a visible effect will occur after the 4th week. LGD-4033 will give you the strength to break your own records in the hall.

Persistence, however, will have to come from within. Serious training with this powerful SARM will help you achieve unprecedented results so far. The cycle should be followed by 4 weeks of rest, accompanied by therapy to normalize natural testosterone production.

To enhance the positive effect of Ligandrol and gain lean muscle mass as quickly as possible, pay attention to your diet. Focus on protein and avoid any fast food as well as sugar.

  • For men - 10 mg once a day, with a cycle duration of 8 to 10 weeks.
  • For women - 5 mg once a day, with a cycle duration of 6 to 8 weeks.

Fat burning cycle

Ligandrol LGD-4033 for fat burning

Although Ligandrol is not known as a SARM for fat burning, a cycle with it can help in this task as well. While gaining muscle mass, LGD-4033 will not allow you to accumulate subcutaneous fat.

For even more amazing results, we recommend combining it with other SARM supplements, such as Cardarine and Andarine. However, with such a stack, the daily dose of Ligandrol should be reduced. Here the rule for 4 weeks rest after the cycle also applies in full force.

  • For men - 5 mg once a day, with a cycle duration of 8 to 10 weeks.
  • For women - 3 mg once a day, with a cycle duration of 6 to 8 weeks.

Post-cycle therapy with Ligandrol LGD4033

Because normal testosterone production in the body will be affected, even to a small degree, therapy is always done after a cycle with Ligandrol.

How you will start treatment after taking LGD-4033 is entirely up to you. Some athletes who use Ligandrol complete the cycle and start herbal therapy, while others rely on the more popular testosterone boosters on the market.

How much the levels of natural testosterone production will fall depends entirely on the intake of this SARM LGD-4033. If you take a minimal dose of Ligandrol, the body will recover very quickly after the cycle.

Ligandrol affects the body's ability to produce testosterone on its own many times less than conventional anabolic steroids. Always take vitamins before and during post-cycle therapy with SARM.

Ligandrol cycle for women

Anabolicum LGD-4033 is suitable for women because it is safe unlike anabolic steroids. The cycle with Ligandrol for women should not last longer than 8 weeks and should not exceed 5 mg per day.

This is one of the most anabolic SARMs and although it has not been studied enough, there are no proven side effects such as virilization (excessive hair growth) in women.

Best SARMs stacks with Ligandrol LGD-4033

Even if used individually, this SARM gives amazing results. There is an increase in muscle mass for about a month, and from the very beginning you feel exceptional endurance.

If you still want to combine Ligandrol with other SARM supplements, see which are the most effective stacks


SARM stack Ligandrol + Ostarine

This is the best stack with Ligandrol. This combination gives excellent results when it comes to gaining lean muscle mass and clearing subcutaneous fat without putting undue strain on the body.

Ostarine raises energy levels, boosts metabolism, and yet has almost no side effects. It will enhance the good results of Ligandrol. In short, this is the lightest but most effective stack with Ligandrol.

In this combination you can take Ligandrol in the recommended doses. 10 mg. per day in men for 8-12 weeks. And for women 5 mg. per day for 6-8 weeks.

SARM stack Ligandrol + Cardarine + Andarine

This stack is suitable for the period when it comes time to melt fat. Ligandrol with the help of Cardarine and Andarine will sculpt the body and make an enviable relief. In this stack, take LGD-4033 5 mg per day or a maximum of 8 mg.

SARM Stack Ligandrol + MK2866 + Cardarine

You will talk about this combination long after the end of the cycle. This SARM stack brings visible results faster than ever. You will notice your muscles shaped and inflated after the second week.

MK2866 or in other words Ostarine will take care of the bones and joints by protecting them from painful injuries. Here, the intake of Ligandrol should not exceed 4 weeks in women and 6 in men.

The good news is that this will not be necessary, because visual changes occur very early. In this case, LGD-4033 is taken 10mg-15mg before breakfast or an hour after a meal.

Ligandrol + vitamins

There are several options to combine Ligandrol with vitamins to feel good during the cycle with it and get the most out of it. In combination with Vitamin B it will protect the liver and increase energy levels even more.

Vitamin D, on the other hand, will make the body more resilient during strenuous physical activity and promote fat loss. Vitamin B12 in combination with Ligandrol boosts metabolism.

How to determine the quality level of Ligandrol

Ligandrol LGD-4033 QUALITY TEST

Ligandrol has been available on the market since 2015. Due to its strong effect, various varieties and different brands have come out. It is not easy to track and determine the level of product quality. Companies that trade in it often abuse the naivety of the customer.

As this is still an experimental product, consumers need to be careful and choose only the best that can be purchased. This will ensure that the effect is exactly as expected and there is no danger to health.

Every user can contact the manufacturer and request quality tests. Always pay attention to whether the product is original and what are the reviews for the brand that sells it.

This will keep you away from counterfeits with harmful substances instead of pure Ligandrol, which can lead to a number of health problems and frustrations.

Where to find a forum for opinions and reviews from Ligandrol (LGD-4033)

There are sites on the Internet where you can find reviews about Ligandrol and reviews of brands that sell it in Bulgaria. This is a sure way to make the best choice for yourself.

Our forum is one such place. There you will find countless opinions of people who have already used Ligandrol and share their achievements in the gym with its help. In the forum you can ask everything you are interested in about SARM supplements, find other people who have similar goals to yours and learn their tricks for better results.

The reviews for Ligandrol there are extremely positive. If you are just entering the world of SARM or you want to try something new, wondering what to combine the LGD-4033 with, or just need more information before making a decision, this is your place.

You can get information from people in the forum who used SARM products and experts in fitness training:

  • Opinions on the benefits of Ligandrol in the short and long term
  • LGD-4033 reviews
  • Opinions and reviews about its side effects
  • Reviews and reviews for the best cycle with Ligandrol?
  • Feedback on whether restorative therapy is mandatory after a cycle with Ligandrol?

What are the side effects of Ligandrol

Ligandrol LGD-4033 side effects

Ligandrol does not have many pronounced side effects, but since it is one of the strongest SARM, it should not be considered completely safe. Each substance in large doses can cause side effects, and each organism is different and may not be tolerant to certain supplements.

SARMs are known to bind directly to androgen receptors in muscle tissue and the entire skeletal system without adversely affecting the liver. Unfortunately, there are no studies that 100% prove this, as it has eaten a new product on the market and is still in clinical development.

Real side effects of Ligandrol

Our forum can help you find out about the side effects of Ligandrol shared by real people. The most common are the following:

  • Suppression of hormones and in particular testosterone production.
  • Migraine
  • Dry mouth

Myths and unrealistic claims about side effects from LGD-4033

You will read and hear many unrealistic claims that this SARM product is just as toxic as anabolic steroids. However, these are myths caused by its proven beneficial effect on increasing muscle mass and strength.

Here are some of the claims about the effect of Ligandrol that are WRONG:

  • Ligandrol is as toxic and damages the liver as steroids
  • Makes the user lethargic
  • Blocks the natural production of testosterone for a long time
  • It has the same side effects as Testosterone

When something cannot be proven, it becomes a myth. We advise you not to believe myths, but always check your eastern ones and watch for current opinions and reviews.

The truth is that hormones after Ligandrol return to normal very quickly, and this has been proven by a number of studies. Ligandrol is not converted to dihydrotestosterone or estrogen (as with Testosterone) and you do not need to use aromasin or others during its use.

How to do therapy after a PCT cycle with Ligandrol

It is recommended to do post-cycle therapy with Ligandrol, either with the use of herbs and vitamins. We recommend that both go hand in hand for even faster recovery.

If the cycle with this SARM has been light and short, PCT may be skipped, but it is always a better idea to support the recovery process. If you have used Ligandrol in normal doses for 8 weeks, you can start 4 weeks of therapy with Clomiphene and / or Nolvadex.


Ligandrol is one of the strongest SARM supplements used by bodybuilders and people striving for greater relief and inflated appearance. Due to its powerful effect on the body, it is banned by the World Doping Agency.

It can be used individually, but also in stack with other SARM supplements, for faster results. LGD-4033 also has a beneficial effect on the skeletal system, preventing injuries. This is a very valuable property, as it gives a lot of strength and endurance in the hall, which can predispose to such incidents.